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ART adherence in resource-poor settings in sub-Saharan Africa: A multi-disciplinary review

Eliud Wekesa, London School of Economics and Political Science (LSE)
Ernestina E. Coast, London School of Economics and Political Science (LSE)

Rationale: In the absence of a cure, antiretroviral therapy (ART) is the only available option with potential to dramatically reduce HIV/AIDS-related mortality and morbidity of PLWHA. Non-adherence to ART significantly compromises its effectiveness. Objectives: To systematically map the factors, at a range of levels (individual-, household-, and community-) associated with ART non-adherence in resource-poor settings. To establish whether traditional models of health-seeking behaviour are appropriate for explaining ART non-adherence. Methods: Multi-disciplinary and multi-method literature mapping of factors associated with non-adherence to ART in resource-poor settings with a focus on sub-Saharan Africa. Results: Preliminary literature mapping reveal a disciplinary emphasis on medical and psychological approaches. Other social sciences are poorly represented in studies of ART adherence. Emerging findings suggest that health-seeking behaviour models, with an emphasis on individual-level factors are inadequate for ART adherence, because they ignore household-, community- and structural-level factors.

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Presented in Poster Session 2